definição e significado de Aminomethyltransferase

Definição

Aminomethyltransferase (n.)

1.(MeSH)A one-carbon group transferase that transfers lipoamide-linked methylamine groups to tetrahydrofolate (TETRAHYDROFOLATES) to form methylenetetrahydrofolate and AMMONIA. It is one of four components of the glycine decarboxylase complex.

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Aminomethyltransferase

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aminomethyltransferase

Crystallographic structure of human AMT.^[1]
Identifiers
Symbol	AMT
Entrez	275
HUGO	AMT 473 AMT
OMIM	238310
PDB	1WSR
RefSeq	NM_000481
UniProt	P48728
Other data
EC number	2.1.2.10
Locus	Chr. 3 p21.2-21.1

Aminomethyltransferase is an enzyme which catabolizes the creation of methylenetetrahydrofolate. It is part of the Glycine decarboxylase complex.

References

^ PDB 1WSR; Okamura-Ikeda K, Hosaka H, Yoshimura M, Yamashita E, Toma S, Nakagawa A, Fujiwara K, Motokawa Y, Taniguchi H (September 2005). [Expression error: Missing operand for > "Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia"]. Journal of Molecular Biology 351 (5): 1146–59. doi:10.1016/j.jmb.2005.06.056. PMID 16051266.

External links

MeSH aminomethyltransferase

This transferase article is a stub. You can help Wikipedia by expanding it.

Transferase: one carbon transferases (EC 2.1)

2.1.1: Methyl-

N-	Histamine N-methyltransferase - Phenylethanolamine N-methyltransferase - Tryptamine N-methyltransferase - Phosphatidylethanolamine N-methyltransferase
O-	5-hydroxyindole-O-methyltransferase/Acetylserotonin O-methyltransferase - Catechol-O-methyl transferase
Homocysteine	Betaine-homocysteine methyltransferase - Homocysteine methyltransferase - 5-Methyltetrahydrofolate-homocysteine methyltransferase
Other	Phosphatidyl ethanolamine methyltransferase - DNMT3B - Histone methyltransferase - Thymidylate synthase - DNA methyltransferase - Thiopurine methyltransferase

2.1.2: Hydroxymethyl-,
Formyl- and Related

Hydroxymethyltransferase	Serine hydroxymethyltransferase - 3-methyl-2-oxobutanoate hydroxymethyltransferase
Formyltransferase	Phosphoribosylglycinamide formyltransferase - Inosine monophosphate synthase - Glutamate formimidoyltransferase
Other	Aminomethyltransferase

2.1.3: Carboxy- and Carbamoyl

Carboxy	methylmalonyl-CoA carboxytransferase
Carbamoyl	Aspartate carbamoyltransferase - Ornithine carbamoyltransferase - Oxamate carbamoyltransferase - Putrescine carbamoyltransferase - 3-hydroxymethylcephem carbamoyltransferase - Lysine carbamoyltransferase - N-acetylornithine carbamoyltransferase

2.1.4: Amidino

Arginine:glycine amidinotransferase

Definição e significado de Aminomethyltransferase

Definição

Definiciones (más)

Sinónimos

Dicionario analógico

Aminomethyltransferase

From Wikipedia, the free encyclopedia

References

External links