From Wikipedia, the free encyclopedia
Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene.[1][2]
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Further reading
- Das S, Maiti T, Das K, Maitra U (1998). [Expression error: Missing operand for > "Specific interaction of eukaryotic translation initiation factor 5 (eIF5) with the beta-subunit of eIF2."]. J. Biol. Chem. 272 (50): 31712–8. doi:10.1074/jbc.272.50.31712. PMID 9395514.
- Bandyopadhyay A, Maitra U (1999). [Expression error: Missing operand for > "Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells."]. Nucleic Acids Res. 27 (5): 1331–7. doi:10.1093/nar/27.5.1331. PMID 9973622.
- Das S, Maitra U (2000). [Expression error: Missing operand for > "Mutational analysis of mammalian translation initiation factor 5 (eIF5): role of interaction between the beta subunit of eIF2 and eIF5 in eIF5 function in vitro and in vivo."]. Mol. Cell. Biol. 20 (11): 3942–50. doi:10.1128/MCB.20.11.3942-3950.2000. PMID 10805737.
- Choi SK, Olsen DS, Roll-Mecak A, et al. (2000). [Expression error: Missing operand for > "Physical and functional interaction between the eukaryotic orthologs of prokaryotic translation initiation factors IF1 and IF2."]. Mol. Cell. Biol. 20 (19): 7183–91. doi:10.1128/MCB.20.19.7183-7191.2000. PMID 10982835.
- Das S, Ghosh R, Maitra U (2001). [Expression error: Missing operand for > "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein."]. J. Biol. Chem. 276 (9): 6720–6. doi:10.1074/jbc.M008863200. PMID 11092890.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). [Expression error: Missing operand for > "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."]. Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
- Asano K, Shalev A, Phan L, et al. (2001). [Expression error: Missing operand for > "Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation."]. Embo J. 20 (9): 2326–37. doi:10.1093/emboj/20.9.2326. PMID 11331597.
- Majumdar R, Bandyopadhyay A, Deng H, Maitra U (2002). [Expression error: Missing operand for > "Phosphorylation of mammalian translation initiation factor 5 (eIF5) in vitro and in vivo."]. Nucleic Acids Res. 30 (5): 1154–62. doi:10.1093/nar/30.5.1154. PMID 11861906.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). [Expression error: Missing operand for > "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."]. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Marintchev A, Kolupaeva VG, Pestova TV, Wagner G (2003). [Expression error: Missing operand for > "Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners."]. Proc. Natl. Acad. Sci. U.S.A. 100 (4): 1535–40. doi:10.1073/pnas.0437845100. PMID 12569173.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). [Expression error: Missing operand for > "Complete sequencing and characterization of 21,243 full-length human cDNAs."]. Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). [Expression error: Missing operand for > "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."]. Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). [Expression error: Missing operand for > "Towards a proteome-scale map of the human protein-protein interaction network."]. Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Homma MK, Wada I, Suzuki T, et al. (2005). [Expression error: Missing operand for > "CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression."]. Proc. Natl. Acad. Sci. U.S.A. 102 (43): 15688–93. doi:10.1073/pnas.0506791102. PMID 16227438.
- Conte MR, Kelly G, Babon J, et al. (2006). [Expression error: Missing operand for > "Structure of the eukaryotic initiation factor (eIF) 5 reveals a fold common to several translation factors."]. Biochemistry 45 (14): 4550–8. doi:10.1021/bi052387u. PMID 16584190.
- Bieniossek C, Schütz P, Bumann M, et al. (2006). [Expression error: Missing operand for > "The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5."]. J. Mol. Biol. 360 (2): 457–65. doi:10.1016/j.jmb.2006.05.021. PMID 16781736.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). [Expression error: Missing operand for > "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."]. Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
PDB Gallery |
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| 2g2k: NMR structure of an N-terminal fragment of the eukaryotic initiation factor 5 (eIF5) |
| 2iu1: CRYSTAL STRUCTURE OF EIF5 C-TERMINAL DOMAIN |
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Protein biosynthesis: translation (prokaryotic, eukaryotic) |
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Ribosomal proteins | | | | |
Archaeal | aIF1 aIF2 aIF5 aIF6 | |
| eIF1 (AX, AY, 1B) eIF2 (α, β, γ) eIF3 (A, B, C, D, F, G, H, I, J, K, M, S6) eIF4 (A2, A3, B, E1, E2, G1, G2, G3, H) eIF5 (A, A2, B) eIF6 |
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